Vitamin D: D2 vs D3, Deficiency, and Who Actually Needs It
Key takeaways D3 (cholecalciferol) raises and maintains blood 25(OH)D levels more effectively than D2 (ergocalciferol) — a meta-analysis of 24 RCTs confirmed higher potency of D3 per equivalent dose (Tripkovic et al., AJCN). Correcting deficiency (25(OH)D <20 ng/mL) has clear benefit; broad supplementation in already-replete adults for cancer, cardiovascular events, or major fractures showed no … Read more