L-Glutamine: Independent Evidence on Leaky Gut, IBS, IBD & Critical Illness Safety
Leaky gut repair? One strong RCT in a narrow IBS subgroup; critical-illness harm signal. Independent evidence, funding traced, evidence graded.
Energy & Focus
Evidence-graded research on energy, fatigue and mitochondrial health — which supplements have real human-trial support, with funding and conflicts disclosed.
Shilajit: Independent Evidence on Testosterone, Energy & Heavy Metal Safety
Mountain mineral pitch — weak data, heavy-metal safety caveat. Independent human-trial evidence, funding traced, evidence graded.
Rhodiola Rosea: Independent Evidence on Stress, Fatigue & Burnout
Adaptogen for burnout? Promising but methodologically weak. Independent human-trial evidence, funding traced, evidence graded.
Lion’s Mane: Independent Evidence on Cognition, Memory & Brain Fog
Brain fog cure? Small pilots, thin human data. Independent human-trial evidence, funding traced, evidence graded.
Bovine Colostrum: Independent Evidence on Gut, Immunity & Skin
Liquid gold for immunity? Athlete URTI data, beauty claims thin. Independent human-trial evidence, funding traced, evidence graded.
Tongkat Ali: Independent Evidence on Testosterone, Libido & Safety
Natural testosterone booster? What human trials actually show. Independent human-trial evidence, funding traced, evidence graded.
NMN Supplements: What the FDA Flip-Flop Means and What the Human Data Actually Shows
Key takeaways NMN reliably raises blood NAD+ in every published human trial, at doses from 100 mg to 1,250 mg/day — that part is well replicated (Yoshino et al. 2021, Science, Yi et al. 2022, GeroScience). What NAD+ elevation actually does for a healthy adult’s function is still thin: a 2024 systematic review of 10 … Read more
Creatine Monohydrate: What 500+ Trials Actually Show (And What the Marketing Gets Wrong)
Key takeaways Strongest evidence: creatine monohydrate at 3-5 g/day increases upper-body strength by roughly 4.4 kg and lower-body strength by roughly 11.4 kg beyond resistance training alone in adults under 50, and produces similar gains in older adults doing resistance training (Burke et al. 2024, Sharifian et al. 2025). Cognitive benefits are real but narrow … Read more
Asthma: Supplements That Work vs Popular Ones With No Evidence
Key takeaways The best-supported “supplement” intervention in asthma isn’t a capsule at all — it’s medically administered IV magnesium sulfate for selected severe acute attacks, per Cochrane (odds ratio 0.10 for admission in the severe subgroup). Vitamin D is reasonable to correct a documented deficiency, but an updated Cochrane review found no evidence it reduces … Read more
Asthma: Prevention and Management — The Complete Evidence-Based Guide
Key takeaways WHO estimates asthma affected 363 million people in 2023 and caused 442,000 deaths, with most deaths linked to under-diagnosis and under-treatment rather than disease severity alone (WHO asthma fact sheet). GINA states SABA-only (reliever-only) treatment raises exacerbation risk, worsens lung function, and increases asthma-death risk — low-dose ICS or as-needed ICS-formoterol cuts severe … Read more