L-Glutamine: Independent Evidence on Leaky Gut, IBS, IBD & Critical Illness Safety
Leaky gut repair? One strong RCT in a narrow IBS subgroup; critical-illness harm signal. Independent evidence, funding traced, evidence graded.
Energy & Focus
Evidence-graded research on energy, fatigue and mitochondrial health — which supplements have real human-trial support, with funding and conflicts disclosed.
Shilajit: Independent Evidence on Testosterone, Energy & Heavy Metal Safety
Mountain mineral pitch — weak data, heavy-metal safety caveat. Independent human-trial evidence, funding traced, evidence graded.
Rhodiola Rosea: Independent Evidence on Stress, Fatigue & Burnout
Adaptogen for burnout? Promising but methodologically weak. Independent human-trial evidence, funding traced, evidence graded.
Lion’s Mane: Independent Evidence on Cognition, Memory & Brain Fog
Brain fog cure? Small pilots, thin human data. Independent human-trial evidence, funding traced, evidence graded.
Bovine Colostrum: Independent Evidence on Gut, Immunity & Skin
Liquid gold for immunity? Athlete URTI data, beauty claims thin. Independent human-trial evidence, funding traced, evidence graded.
Tongkat Ali: Independent Evidence on Testosterone, Libido & Safety
Natural testosterone booster? What human trials actually show. Independent human-trial evidence, funding traced, evidence graded.
NMN Supplements: What the FDA Flip-Flop Means and What the Human Data Actually Shows
Key takeaways NMN reliably raises blood NAD+ in every published human trial, at doses from 100 mg to 1,250 mg/day — that part is well replicated (Yoshino et al. 2021, Science, Yi et al. 2022, GeroScience). What NAD+ elevation actually does for a healthy adult’s function is still thin: a 2024 systematic review of 10 … Read more
Creatine Monohydrate: What 500+ Trials Actually Show (And What the Marketing Gets Wrong)
Key takeaways Strongest evidence: a meta-analysis in adults under 50 found average additional upper-body strength gains of roughly 4.4 kg and lower-body gains of roughly 11.4 kg with creatine plus resistance training versus placebo plus training. Doses and protocols varied; these are pooled averages, not guaranteed individual gains. A separate review supports strength benefits in … Read more
Asthma: Supplements That Work vs Popular Ones With No Evidence
Key takeaways The best-supported “supplement” intervention in asthma isn’t a capsule at all — it’s medically administered IV magnesium sulfate for selected severe acute attacks, per Cochrane (odds ratio 0.10 for admission in the severe subgroup). Vitamin D is reasonable to correct a documented deficiency, but an updated Cochrane review found no evidence it reduces … Read more
Asthma: Prevention and Management — The Complete Evidence-Based Guide
Key takeaways WHO estimates asthma affected 363 million people in 2023 and caused 442,000 deaths, with most deaths linked to under-diagnosis and under-treatment rather than disease severity alone (WHO asthma fact sheet). GINA states SABA-only (reliever-only) treatment raises exacerbation risk, worsens lung function, and increases asthma-death risk — low-dose ICS or as-needed ICS-formoterol cuts severe … Read more