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Articles by Pure City Research

Research and evidence summaries published by the Pure City Research editorial team.

Rheumatoid Arthritis: Independent Evidence on DMARDs, Omega-3, Curcumin & Supplements

July 6, 2026 by Pure City Research

DMARDs are standard of care; omega-3 fish oil is the best-supported supplement adjunct. Independent human-trial evidence, funding traced.

Categories Autoimmune & Inflammatory, Heart & Cardiovascular, Rheumatoid Arthritis

Sinus Issues (Chronic Rhinosinusitis): Independent Evidence on Saline, Steroids & Supplements

July 20, 2026July 6, 2026 by Pure City Research

Saline irrigation is the strongest non-drug intervention; most supplements lack CRS evidence. Independent human-trial evidence, funding traced.

Categories Asthma & Respiratory, Chronic Rhinosinusitis, Gut & Digestion

Narcolepsy: Independent Evidence on Treatments, Supplements & Safety

July 6, 2026 by Pure City Research

Excessive daytime sleepiness & cataplexy — evidence-based treatments are prescription drugs; no supplement has adequate evidence. Independent human-trial evidence, funding traced.

Categories Narcolepsy, Neurology & Brain Health, Sleep

Natural vs Chemicals: Why Natural Doesn’t Always Mean Safe

July 20, 2026July 6, 2026 by Pure City Research

Natural doesn’t mean safe (botulinum, ricin, aflatoxin, ephedra); chemical doesn’t mean dangerous (creatine, caffeine, sucralose). The dose makes the poison.

Categories Natural vs Organic

Natural vs Organic Certified: Why Organic Reduces Contaminants & Why EU Organic Is Safer

July 4, 2026 by Pure City Research

‘Natural’ has no legal definition; organic is certified — but neither is proven healthier. Independent evidence, funding traced, evidence graded.

Categories Gut & Digestion, Natural vs Organic

Zinc-L-Carnosine (Polaprezinc): Independent Evidence on Gastric Ulcer, H. pylori & Mucositis

July 4, 2026 by Pure City Research

Gastric ulcer healing and H. pylori adjunct — Japan drug, US supplement. Independent evidence, funding traced, evidence graded.

Categories Gut & Digestion, Zinc-L-Carnosine

L-Glutamine: Independent Evidence on Leaky Gut, IBS, IBD & Critical Illness Safety

July 8, 2026July 4, 2026 by Pure City Research

Leaky gut repair? One strong RCT in a narrow IBS subgroup; critical-illness harm signal. Independent evidence, funding traced, evidence graded.

Categories Energy & Focus, Gut & Digestion, L-Glutamine

Shilajit: Independent Evidence on Testosterone, Energy & Heavy Metal Safety

July 4, 2026July 4, 2026 by Pure City Research

Mountain mineral pitch — weak data, heavy-metal safety caveat. Independent human-trial evidence, funding traced, evidence graded.

Categories Energy & Focus, Muscle Building, Shilajit

Rhodiola Rosea: Independent Evidence on Stress, Fatigue & Burnout

July 20, 2026July 4, 2026 by Pure City Research

Adaptogen for burnout? Promising but methodologically weak. Independent human-trial evidence, funding traced, evidence graded.

Categories Energy & Focus, Rhodiola, Stress, Anxiety & Depression

Lion’s Mane: Independent Evidence on Cognition, Memory & Brain Fog

July 4, 2026July 4, 2026 by Pure City Research

Brain fog cure? Small pilots, thin human data. Independent human-trial evidence, funding traced, evidence graded.

Categories Energy & Focus, Lion's Mane, Stress, Anxiety & Depression
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