CGRP Migraine Drugs: Independent Evidence, Safety & Cost
Erenumab, fremanezumab, galcanezumab, eptinezumab, rimegepant and atogepant: what independent reviews show on benefit, blood pressure, Raynaud’s, constipation and cost.
Neurology & Brain Health
Sodium Valproate: Independent Evidence on Epilepsy & Pregnancy
Sodium valproate (Epilim, Depakote): what independent trials show for epilepsy and mania, the birth-defect and neurodevelopmental risks, UK rules, the Cumberlege review and who funds the evidence.
Multiple Sclerosis: Drug, Vitamin D & Diet Evidence and Funding
How MS is diagnosed and treated, what vitamin D and diet trials show, and who paid for the drug trials, prices and settlements behind the evidence.
Parkinson’s Disease: Independent Evidence on Treatment & Funding
Levodopa works for symptoms; no drug or supplement is proven to slow Parkinson’s. We grade the trials on treatment, DBS, exercise and who funded them.
Epilepsy: Independent Evidence on Treatment, Pregnancy & Funding
Epilepsy diagnosis, medicines, pregnancy risks, SUDEP, driving, surgery, diet and cannabidiol, graded by independent evidence, with the funding behind each trial.
Ginkgo, Bacopa and Memory Supplements: Independent Evidence
Ginkgo did not prevent dementia in two large trials. We grade ginkgo, bacopa, citicoline and Prevagen claims, bleeding risks and who funded the evidence.
Donepezil and Memantine: Independent Evidence, Risks & Funding
Donepezil, rivastigmine, galantamine and memantine for dementia: AD2000, Cochrane, NICE, heart and fainting risks, stopping evidence and who funded the trials.
Lecanemab and Donanemab: Independent Evidence, ARIA Risk & Cost
Anti-amyloid antibodies for early Alzheimer’s: trial effect sizes, ARIA brain swelling, ApoE4 risk, regulators, NICE and who funded the evidence.
Triptans: Independent Evidence on Migraine, Heart Risk & Safety
Independent review of triptans for acute migraine: Cochrane and BMJ evidence, heart and stroke risk, the serotonin syndrome alert, overuse headache, pregnancy and funding.
Gabapentin: Independent Evidence on Pain, Epilepsy & Misuse Risk
Gabapentin (Neurontin): what independent reviews show for nerve pain and epilepsy, why off-label use outran the evidence, opioid and breathing risks, and who funded it.